| Topo II Inhibitor Resistance Marker | ||||
|---|---|---|---|---|
| Marker | Name | Biological Role | Evidence | References |
| PGP (MDR1, ABCB1) | P-Glycoprotein; multi-drug resistance protein 1 | ATP-binding cassette transporter and drug efflux pump for anthracyclines | High expression associated with poor responses and outcomes to doxorubicin therapy in ovarian cancer | TopoII Inhibitor Resistance: PGP References |
