| cMET Inhibitor Sensitivity Markers | ||||
|---|---|---|---|---|
| Marker | Name | Biological Role | Evidence | References |
| cMET | Mesenchymal-epithelial transition receptor | HGF-activated membrane receptor tyrosine kinase that phosphorylates itself and initiates a cascade of signaling events that lead to increased cell proliferation, motility, invasion, and survival | Amplification of the cMET gene correlates with response to crizotinib in esophago-gastric cancer | cMET inhibitor sensitivity: cMET reference |
