| BRAF Inhibitor Sensitivity Markers | ||||
|---|---|---|---|---|
| Marker | Name | Biological Role | Evidence | References |
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | Serine/threonine protein kinase that regulates MEK and MAPK (ERK) signaling pathway | BRAF V600 mutation activates the kinase activity leading to independence from KRAS GTPase function | BRAF inhibitor sensitivity: BRAF references |
